| Information | |
|---|---|
| has gloss | (noun) a class of transferases that catalyze transamination (that transfer an amino group from an amino acid to another compound) transaminase, aminotransferase, aminopherase |
| has gloss | eng: In biochemistry, a transaminase or an aminotransferase is an enzyme that catalyzes a type of reaction between an amino acid and an α-keto acid. Specifically, this reaction (transamination) involves removing the amino group from the amino acid, leaving behind an α-keto acid, and transferring it to the reactant α-keto acid and converting it into an amino acid. The enzymes are important in the production of various amino acids, and measuring the concentrations of various transaminases in the blood is important in the diagnosing and tracking many diseases. Transaminases require the coenzyme pyridoxal-phosphate, which is converted into pyridoxamine in the first phase of the reaction, when an amino acid is converted into a keto acid. Enzyme-bound pyridoxamine in turn reacts with pyruvate, oxaloacetate, or alpha-ketoglutarate, giving alanine, aspartic acid, or glutamic acid, respectively. |
| lexicalization | eng: aminopherase |
| lexicalization | eng: aminotransferase |
| lexicalization | eng: transaminase |
| subclass of | (noun) any of various enzymes that move a chemical group from one compound to another compound transferase |
| has subclass | (noun) an enzyme involved in transamination glutamic oxalacetic transaminase, glutamic oxaloacetic transaminase |
| Meaning | |
|---|---|
| Catalan | |
| has gloss | cat: Les aminotransferases (o transaminases) són un conjunt denzims del grup de les transferases, ja que transfereixen grups amino des dun metabòlit a un altre, generalment aminoàcids. Aquests enzims són induïbles, perquè la seva activitat pot augmentar per lacció de diverses hormones com la tiroxina o els glucocorticoides, la seva reacció és lliurement reversible i la seva constant dequilibri és a prop a la unitat. |
| lexicalization | cat: Aminotransferasa |
| German | |
| has gloss | deu: Aminotransferasen oder Transaminasen sind substratspezifische Enzyme, welche die Übertragung von α-Aminogruppen von einem Donor- auf ein Akzeptormolekül katalysieren (Transaminierung). Üblicherweise handelt es sich bei dem Donor um eine Aminosäure und bei dem Akzeptor um eine α-Ketosäure, wobei aus der Aminosäure eine neue α-Ketosäure und aus der ursprünglichen α-Ketosäure eine neue Aminosäure wird. |
| lexicalization | deu: Aminotransferase |
| Basque | |
| has gloss | eus: Transaminasak entzima mota bat dira, amino taldearen transferentzia-erreakzioak katalizatzen dituztenak. Amino talde hori (-NH2) aminoazido batetik zetoazido batera pasatu ohi da, ekuazio honen arabera: |
| lexicalization | eus: transaminasa |
| French | |
| has gloss | fra: Une transaminase ou aminotransférase est une enzyme qui catalyse un type de réaction entre un acide aminé et un acide α-cétonique. Biochimie Enzyme à pyridoxal phosphate de la classe des transférases, elle effectue le transfert dun groupement -NH2 dun acide aminé vers un autre, permettant la synthèse de nouveaux acides aminés, non présents dans le milieu. |
| lexicalization | fra: transaminase |
| Croatian | |
| has gloss | hrv: Transaminaze ili aminotransferaze (u biokemiji) je naziv za enzime koji kataliziraju reakciju između aminokiseline i alfa-ketokiselina. |
| lexicalization | hrv: Transaminaze |
| Italian | |
| has gloss | ita: Le transaminasi (o amminotransferasi) sono una sotto-sottoclasse di enzimi (appartenenti alla classe delle transferasi e aventi ) predisposti a catalizzare la reazione di trasferimento del gruppo amminico α da un amminoacido a un α-chetoacido. |
| lexicalization | ita: transaminasi |
| lexicalization | ita: aminotransferasi |
| Japanese | |
| has gloss | jpn: アミノ基転移酵素（あみのきてんいこうそ、EC 2.6.1）とは、生化学においてアミノ酸とα-ケト酸の間の反応を触媒する酵素の総称である。トランスアミナーゼ（transaminase）またはアミノトランスフェラーゼ）aminotransferase）とも呼ばれる。 |
| lexicalization | jpn: アミノ基転移酵素 |
| lexicalization | jpn: トランスアミナーゼ |
| lexicalization | jpn: 転移酵素 |
| Dutch | |
| Show unreliable ▼ | |
| lexicalization | nld: transaminase |
| Polish | |
| has gloss | pol: Aminotransferazy lub transaminazy - określenia stosowane w terminologii medycznej w odniesieniu dwóch enzymów wskaźnikowych: AlAT i AspAT, które mają istotne znaczenie w diagnostyce medycznej. |
| lexicalization | pol: Aminotransferazy |
| Portuguese | |
| has gloss | por: A transaminase é uma enzima que catalisa especificamente a reação de transaminação. Exemplos como a aspartato aminotransferase (AST, anteriormente designada SGOT ou TGO -transaminase glutâmica oxalacética ) e alanina aminotransferase (ALT, antes SGPT ou TGP -transaminase glutâmica pirúvica ) estão amplamente distribuídas nas células, especialmente no fígado e no miocárdio, além de estar presente nos rins e músculo esquelético, mas sua taxa sanguínea é baixa. Esta taxa se eleva consideravelmente em caso de lesões celulares. O aumento do teor de AST pode indicar enfarte do miocárdio e o de ALT, lesão hepática. |
| lexicalization | por: transaminase |
| lexicalization | por: aminotransferase |
| Russian | |
| has gloss | rus: Аминотрансфера́зы (трансаминазы) — ферменты из группы трансфераз, переносящие группы атомов, содержащие азот. Аминотрансферазы также называют трансаминазами. |
| lexicalization | rus: Аминотрансферазы |
| Castilian | |
| has gloss | spa: Las aminotransferasas (o transaminasas) son un conjunto de enzimas del grupo de las transferasas, pues transfieren grupos amino desde un metabolito a otro, generalmente aminoácidos. Estas enzimas son inducibles, porque su actividad puede aumentarse por la acción de diversas hormonas como la tiroxina o los glucocorticoides, su reacción es libremente reversible y su constante de equilibrio está cerca a la unidad. |
| lexicalization | spa: aminotransferasa |
| lexicalization | spa: transaminasa |
| Links | |
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| similar | e/Transaminase |
| Media | |
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| media:img | Aspartate transaminase.png |
| media:img | Transaminierung.svg |
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