| Information | |
|---|---|
| has gloss | (noun) antihypertensive drug (trade name Minipress) prazosin, Minipress |
| has gloss | eng: Prazosin, trade names Minipress,Vasoflex and Hypovase, is a sympatholytic drug used to treat high blood pressure (hypertension). It belongs to the class of alpha-adrenergic blockers, which lower blood pressure by relaxing blood vessels. Specifically, prazosin is selective for the alpha-1 receptors on vascular smooth muscle. These receptors are responsible for the vasoconstrictive action of norepinephrine, which would normally raise blood pressure. By blocking these receptors, prazosin reduces blood pressure. |
| lexicalization | eng: Minipress |
| lexicalization | eng: prazosin |
| subclass of | (noun) any of various drugs that block alpha-adrenergic receptors; used in treating benign prostatic hyperplasia; relaxes the muscles of the prostate and bladder alpha-adrenergic blocking agent, alpha blocker, alpha-adrenergic blocker, alpha-blocker |
| subclass of | (noun) a drug that reduces high blood pressure antihypertensive drug, antihypertensive |
| Meaning | |
|---|---|
| German | |
| has gloss | deu: Prazosin ist ein Arzneistoff aus der Gruppe der α-Adrenozeptorantagonisten (α-Blocker). Wie seine pharmakologischen Verwandten Terazosin und Doxazosin wird er vorrangig zur Behandlung der arteriellen Hypertonie eingesetzt. Prazosin wird auch bei Patienten, die an dem Raynaud-Syndrom (Durchblutungsstörungen in den Fingern) leiden, angewandt. Ferner kann es bei benigner Prostatahyperplasie (BPH) eingesetzt werden, um den Harnabfluss zu verbessern; allerdings existieren zu diesem Zweck selektivere Arzneistoffe mit weniger unerwünschten systemischen Wirkungen (z. B. Tamsulosin). Prazosin wurde 1969 von Pfizer patentiert und ist auch als Generikum im Handel. |
| lexicalization | deu: Prazosin |
| French | |
| has gloss | fra: La prazosine est un médicament antihypertenseur. Il appartient à la classe des alpha-bloquants, qui abaissent la tension artérielle par le relâchement des vaisseaux sanguins. La prazosine est sélective pour les récepteurs alpha1 sur les muscles lisses vasculaires. Ces récepteurs sont responsables de l'action vasoconstrictive de la noradrénaline, qui a son tour élève la tension sanguine. En bloquant ces récepteurs, la prazosine abaisse la tension. |
| lexicalization | fra: prazosine |
| Croatian | |
| has gloss | hrv: Prazosin, kao i doksazosin spada u selektivne blokatore alfa-1 adrenergičkih receptora. |
| lexicalization | hrv: prazosin |
| Japanese | |
| has gloss | jpn: プラゾシン（）は、アドレナリン作動性効果遮断薬のひとつ。α1受容体を選択的に遮断する。慢性高血圧の治療に使用され、副作用として起立性低血圧が生じる。 |
| lexicalization | jpn: プラゾシン |
| Portuguese | |
| has gloss | por: Prazosin é um medicamento relacionado com o controle da hipertensão. Bloqueia receptores alfa-adrenérgicos pós-sinápticos da terminação nervosa simpática. |
| lexicalization | por: Prazosin |
| Links | |
|---|---|
| similar | e/Minipress |
| similar | e/Prazosin |
| Media | |
|---|---|
| media:img | Prazosin.svg |
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