| Information | |
|---|---|
| has gloss | (noun) abnormally large red blood cell present in pernicious anemia and folic acid deficiency megaloblast |
| has gloss | eng: A megaloblast is an unusually large erythroblast that can be associated with pernicious anemia (Vitamin B12 deficiency) and folic acid deficiency (collectively called megaloblastic anemia). It is differentiated from a normoblast, which is a normally-sized erythroblast. This kind of anemia leads to macrocytes (abnormally large red cells). The cause of this cellular gigantism is an impairment in DNA synthesis which delays nuclear maturation and cell division. Because RNA and cytoplasmic elements are synthesized at a constant rate despite the cells impaired DNA synthesis the cells show nuclear-cytoplasmic asynchrony. |
| lexicalization | eng: megaloblast |
| subclass of | (noun) a mature blood cell that contains hemoglobin to carry oxygen to the bodily tissues; a biconcave disc that has no nucleus red blood cell, RBC, erythrocyte |
| Meaning | |
|---|---|
| Catalan | |
| has gloss | cat: Un megaloblast és un eritroblast inusualment gran que pot estar associat amb lanèmia perniciosa (deficiència de vitamina B12) i la deficiència dàcid fòlic (anomenats en conjunt l'anèmia megaloblàstica). |
| lexicalization | cat: Megaloblast |
| lexicalization | cat: megaloblast |
| German | |
| has gloss | deu: Als Megaloblasten werden ungewöhnlich große, kern- und hämoglobinhaltige Vorläuferzellen der Erythrozyten im Knochenmark bezeichnet. Sie entwickeln sich aus dem noch hämoglobinfreien Promegaloblasten. Die reifen, vergrößerten Erythrozyten werden entsprechend auch Megalozyten genannt. |
| lexicalization | deu: Megaloblast |
| Italian | |
| lexicalization | ita: megaloblasto |
| Links | |
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| similar | e/Megaloblast |
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